Master Chief John-117 and a defected elite find they have been deposited on a world of talking, technicolor ponies, who they will have to protect with all they have. (based from Halo 4, but there are plot twists)
When the Power Ponies fail to stop the Mane-iac from using her Doomsday device, what will happen? Of all the things to stop the Mane-iac, a human seems the least likely to do so.
After an AMC Javelin is launched through ponyville after an unexplainable magical event, the ponies have no clue just what to do with it. Or the human found unconscious nearby..
Twilight sparkle casts a spell incorrectly, and is transported to a silent, dead world. Can she figure out how to return to equestria while returning sound to the world she was deposited in?
The TADA (Temporal Adjustment and Displacement Agency) deals with any being that either is somehow temporally displaced, or an entity that is adjusting the events of time for any sort of reason, from evil to benign.
Search for Extant, Near-Transition Intelligence on Exoplanets Near Cluster E672-b. "SENTIENCE" was the designation for a swarm of nanites that were launched through space.
Black Magic (My OC) has run away from everything he used to know in Manehatten, and into the Everfree Forest. When he exits the forest two years later, he ends up in a small, yet lively town called Ponyville.