Twilight is a smart and independent pony who has no interest in making friends. That might be because of the experience she had when arriving to Ponyville

A dog has been abandoned by his owner

Rainbow Dash borrows Applejack's money more and more till things get out of hand.

I think the title speaks for itself

The zombie apocalypse got the Mane 6 and Spike and Celestia and Luna try to stop this madness.

Rainbow Dash tries to complete Minecraft while Applejack and Pinkie Pie chase her.

Pinkie starts ordering briskets and things start to get crazy as she orders more.

Sunset battles Fluttershy on Pokémon Showdown

A mysterious pony helps Zephyr to get his life together. Sweet, innocent Zephyr didn't know what the consequence was

You work five nights at the Equestria Girls' Cupcake Corner.

Trixie battles her replica in a magic duel.

A family orders the Amazon Echo that replies in the voice of one of the members of the Dazzlings

Rainbow Dash sees signs correlating to things she just said.

Basically, you start a Pokémon adventure however you also get to use MLP characters as Pokémon

Twilight and Spike go on a journey to get ideas for her story