When Equestria appeared on Earth, there were some that did not appreciate the equine arrivals. Some that took grave offense at ponification.
Thanks to attitudes like that, Equestrians and Humans alike have all suffered in some way or another.
It all ends. Today, Equestria is removed from the face of the Earth despite the protestations and best efforts of the pony sisters, and Humans finally get their victory.
But at what cost?