Mewtwo, the clone of the mythical Mew. An ancient experiment that was forgotten in history, has returned to claim the throne and wants to rule all of Pony kind.

The Mane Six, the once-great heroes that saved Equestria from threats such as Tirek, Discord, Starlight Glimmer and so many others. Now, they're shells of their former glory. Falling victim to Mewtwo's unlimited psychic power.

With a situation like this, you'd believe there's no hope left for Equestria. Well, a certain Draconuqeus, two Ponies and a Changeling King don't believe that in the slightest! Now, it's time for the reformed to strike back against Mewtwo's tyranny, once and for all.