Three teams of ponies compete in "The Best Friends Game", a travelling game show that roams around Equestria in which contestants predict the answers their friends will give to interesting questions to win the grand prize! The teams are:
1) Lyra and Bon Bon
2) Doctor Whooves and Derpy Hooves
3) Cranky Doodle Donkey and Matilda
In case you couldn't tell, this is a loose parody of the show, "The Newlywed Game".
Vectors used in Cover Art:
http://mlp-vectorclub.deviantart.com/art/Bon-Bon-Angry-Snout-Scrunch-398003901
http://alf-img.com/show/lyra-pony-mad.html