Boltstrike58 fed her something funky.

probably vanilla extract.

Pinkie Pie barfed again into the toilet bowl.

"Seriously," Spike placed another roll of toilet paper beside her. "What did you even eat that made you like this?"

Pinkie coughed, groggily lifting her head.

"Vanilla extract."

She threw up again.

"That doesn't even make sense! That stuff gives you alcohol poisoning, not food poisoning!"