Twilight's magical skill had greatly improved with Princess Celestia as her teacher and mentor as the years soared by. However, she has been scarred by her deadly accident that happened on the day of her enrollment test, thus never really fully recovering from the incident. She was almost always tired, weak, and paranoid. A few times, she even fell into depression. Discovering what friendship could be and making friends with the rest of the Elements of Harmony had somewhat helped her, but she still struggled greatly. She was lucky that the Mane Six had managed to stop Nightmare Moon from  deploying Eternal Night, and stop Discord from wrecking havoc in Ponyville with his power of Chaos.

One day, Twilight was walking with her friends, Applejack, and Rarity to Sugar Cube Corner, for some cupcakes and tea. Applejack and Rarity had to help Twilight stay on her hooves due to her mild fatigue, but otherwise, the unicorn was having one of her good days.

The three ponies entered the Sweet Shop to be greeted by an excited Pinkie Pie, who had realized she should probably take it down a notch since Twilight was there. She didn't want to do any harm to her by accident. They all sat down, except for Pinkie, who was taking her guests orders. After the orders were placed, she went into the kitchen to bake the cupcakes with the Cakes.

After a few moments of silence, Twilight spoke up, "I'm very glad you two brought me out here today. Thanks."

"Sure thing, Twigh!" Applejack replied, "No trouble at all!"

"It certainly is a lovely day for this," Rarity added.

Twilight smiled. She was grateful that her friends at her side to help with her troubles. If it weren't for them, who knows how she'd be right now?

Pinkie Pie came back out from the kitchen with four, delicious looking cupcakes and four cups of tea on a tray. She sat down with her friends and they ate, chatted happily.

And to think nothing would go wrong.

After some time, Twilight felt a slight pulse of pain in the base of her horn, but it went away after a split-second. She was about to take another bite out of her cupcake when the pain came back, this time feeling worse.

"Ow..." the unicorn muttered, rubbing her forehead.

Applejack looked towards her in concern, "You okay there, sugar cube?"

"I'm fine," Twilight answered, "It's just-- Owwwwwww!"

The poor unicorn fell of her chair and onto the ground, clutching her head in pain. The other three ponies quickly knelt down to Twilight and tried to help her. Applejack's eyes started to fill with tears, while Rarity held Twilight in her arms and hummed a soothing song to help reduce the stress on the purple unicorn, and Pinkie's hair slowly started to fall straight.

Meanwhile, back in Canterlot, sat Princess Celestia in her throne, eyes closed, as if she were in meditation. Her eyes suddenly shot open wide.

"Twilight...." She whispered....

"NO!!!"